Role of Cited2 and HIF1a in Heart Development
Coronary Vessel Development and Other Organ Systems
Yin Z, Haynie J, Yang X, Han B, Kiatchoosakun S, Restivo J, Yuan S, Conlon R, Hoit, B, Watanabe M, Yang Y.-C. (2002) Essential role of Cited2, a p300/CBP interaction protein, in heart development and neurulation. PNAS USA 99(16), 10488-10493.
Xu, B, Doughman Y-Q, Turakhia M, Semenza GL, Watanabe M (co-corresponding author), Yang, Y-C (2007) Partial rescue of defects in Cited2-deficient embryos by HIF1-alpha heterozygosity. Dev Biol 301(1), 130-140. PMCID:PMC24673.
Wikenheiser J, Doughman Y-Q, Fisher SA, Watanabe M. (2006) Differential levels of hypoxia in the developing chicken heart. Dev Dyn 235(1), 115-123.
Qu X, Lam E, Doughman YQ, Chen Y, Chou Y-T, Lam M, Turakhia M, Dunwoodie SL, Watanabe M, Xu B, Duncan SA, Yang Y-C (2007) Cited2, a coactivator of HNF4a is essential for liver development. EMBO J 26(21), 4445-4456. PMID: 17932483, PMCID: PMC2063472.
Xu, B, Qu X, Gu S, Doughman Y-Q, Watanabe M, Yang Y-C. (2008) Cited2 is required for fetal lung maturation. Developmental Biology 317(1), 95-105. PMID: 18358466, PMCID: PMC2467387.
Chen Y, Doughman Y-Q, Gu S, Jarrell A, Aota S, Cveki A, Watanabe M, Dunwoodie S, Johnson RS,van Heyningen V, Kleinjan D, Beebe D, Yang Y-C. (2008) Cited2 is required for the proper formation of the hyaloid vasculature and lens morphogenesis. Development 135 (17), 2939-2948, PMCID: PMC2654719.
Yang K, Doughman YQ, Karunamuni G, Gu S, Yang Y-C, Watanabe M. (2009) Expression of active Notch1 in avian coronary development. Dev Dyn 238(1), 162-170. PMID 19097050. PMID:PMC2929638.
Wikenheiser J, Wolfram J, Gargesha M, Yang K, Karunamuni G, Wilson DL, Semenza GL, Agani F, Fisher SA, Ward N, Watanabe M. (2009) Altered hypoxia-inducible factor-1 alpha expression levels correlate with coronary vessel anomalies. Dev Dyn 238(10), 2688-2700. PMID 1977592.
Huang TQ, Wang Y, Ebrahem Q, Chen Y, Cheng C, Doughman YQ, Watanabe M, Dunwoodie SL, Yang YC (2012) Deletion of HIF-1α partially rescues the abnormal hyaloid vascular system in Cited2 conditional knockout mouse eyes. Mol Vis. 2012;18:1260-70. Epub 2012 May 11. PMID: 22665973. PMC3365139
Wikenheiser J, Karunamuni G, Sloter E, Walker MK, Roy D, Wilson DL, Watanabe M (2013) Altering HIF-1a through 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) exposure affects coronary vessel development. In Press in Cardiovascular Toxicology. PMID: 23264063 [ePub].
Tao J, Doughman YQ, Yang K, Ramirez-Bergeron D, Watanabe M (2013) Epicardial HIF signaling regulates vascular precursor cell invasion into the myocardium In Press in Development Biology. PMC444961
Xu, B, Doughman Y-Q, Turakhia M, Semenza GL, Watanabe M (co-corresponding author), Yang, Y-C (2007) Partial rescue of defects in Cited2-deficient embryos by HIF1-alpha heterozygosity. Dev Biol 301(1), 130-140. PMCID:PMC24673.
Wikenheiser J, Doughman Y-Q, Fisher SA, Watanabe M. (2006) Differential levels of hypoxia in the developing chicken heart. Dev Dyn 235(1), 115-123.
Qu X, Lam E, Doughman YQ, Chen Y, Chou Y-T, Lam M, Turakhia M, Dunwoodie SL, Watanabe M, Xu B, Duncan SA, Yang Y-C (2007) Cited2, a coactivator of HNF4a is essential for liver development. EMBO J 26(21), 4445-4456. PMID: 17932483, PMCID: PMC2063472.
Xu, B, Qu X, Gu S, Doughman Y-Q, Watanabe M, Yang Y-C. (2008) Cited2 is required for fetal lung maturation. Developmental Biology 317(1), 95-105. PMID: 18358466, PMCID: PMC2467387.
Chen Y, Doughman Y-Q, Gu S, Jarrell A, Aota S, Cveki A, Watanabe M, Dunwoodie S, Johnson RS,van Heyningen V, Kleinjan D, Beebe D, Yang Y-C. (2008) Cited2 is required for the proper formation of the hyaloid vasculature and lens morphogenesis. Development 135 (17), 2939-2948, PMCID: PMC2654719.
Yang K, Doughman YQ, Karunamuni G, Gu S, Yang Y-C, Watanabe M. (2009) Expression of active Notch1 in avian coronary development. Dev Dyn 238(1), 162-170. PMID 19097050. PMID:PMC2929638.
Wikenheiser J, Wolfram J, Gargesha M, Yang K, Karunamuni G, Wilson DL, Semenza GL, Agani F, Fisher SA, Ward N, Watanabe M. (2009) Altered hypoxia-inducible factor-1 alpha expression levels correlate with coronary vessel anomalies. Dev Dyn 238(10), 2688-2700. PMID 1977592.
Huang TQ, Wang Y, Ebrahem Q, Chen Y, Cheng C, Doughman YQ, Watanabe M, Dunwoodie SL, Yang YC (2012) Deletion of HIF-1α partially rescues the abnormal hyaloid vascular system in Cited2 conditional knockout mouse eyes. Mol Vis. 2012;18:1260-70. Epub 2012 May 11. PMID: 22665973. PMC3365139
Wikenheiser J, Karunamuni G, Sloter E, Walker MK, Roy D, Wilson DL, Watanabe M (2013) Altering HIF-1a through 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) exposure affects coronary vessel development. In Press in Cardiovascular Toxicology. PMID: 23264063 [ePub].
Tao J, Doughman YQ, Yang K, Ramirez-Bergeron D, Watanabe M (2013) Epicardial HIF signaling regulates vascular precursor cell invasion into the myocardium In Press in Development Biology. PMC444961
